Difference between revisions of "Part:BBa K5531012"
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Revision as of 04:05, 30 September 2024
P4H
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
BBa_K5531012 (P4H)
Profile
Name: P4H
Base Pairs: 738 bp
Origin: Arabidopsis thaliana (Mouse-ear cress); synthesized
Properties: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins. Hydroxylates preferentially prolines in the second positions in the -Pro-Pro-Gly-triplets. Hydroxyprolines are essential constituents of many plant cell wall glycoproteins, such as extensions, hydroxyproline-rich glycoproteins, lectins, and arabinogalactan proteins. Can hydroxylate collagen-like peptides and hypoxia-inducible transcription factor peptides [1].
References
[1] Rutschmann C, Baumann S, Cabalzar J, Luther KB, Hennet T. Recombinant expression of hydroxylated human collagen in Escherichia coli. Appl Microbiol Biotechnol. 2014 May;98(10):4445-55.