Difference between revisions of "Part:BBa K5311006"

 
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The CAP 10-3 endolysin is an enzyme derived from a bacteriophage that specifically targets and lyses Cutibacterium acnes. Its inclusion in our project is essential, as it allows us to regulate the growth of Cutibacterium acnes, ensuring a balanced interaction between the patient’s original skin microbiota and the newly introduced microbiota from our product, thereby preventing dysbiosis.
  
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The primary function of this enzyme is to induce cell death in the transformed Cutibacterium acnes. It achieves this by degrading the peptidoglycan links in the bacterial cell wall, creating pores that destabilize the cell membrane. Ultimately, the exposed Cutibacterium acnes cells succumb to osmotic pressure, leading to their death.[1]

Revision as of 09:14, 26 September 2024

CAP 10-3 Endolysin The CAP 10-3 endolysin is an enzyme derived from a bacteriophage that specifically targets and lyses Cutibacterium acnes. Its inclusion in our project is essential, as it allows us to regulate the growth of Cutibacterium acnes, ensuring a balanced interaction between the patient’s original skin microbiota and the newly introduced microbiota from our product, thereby preventing dysbiosis.

The primary function of this enzyme is to induce cell death in the transformed Cutibacterium acnes. It achieves this by degrading the peptidoglycan links in the bacterial cell wall, creating pores that destabilize the cell membrane. Ultimately, the exposed Cutibacterium acnes cells succumb to osmotic pressure, leading to their death.[1]