Difference between revisions of "Part:BBa K5058000"
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The ADH2 promoter is a well-characterized and widely used regulatory element in Saccharomyces cerevisiae that controls the expression of the alcohol dehydrogenase 2 gene. Its activity is tightly regulated by glucose levels, exhibiting repression during high glucose conditions and strong induction during glucose depletion, making it a key component in metabolic and synthetic biology applications. Due to its glucose-repressible nature, the ADH2 promoter is frequently employed in metabolic engineering strategies to drive gene expression in the later stages of fermentation, allowing for a temporal control. | The ADH2 promoter is a well-characterized and widely used regulatory element in Saccharomyces cerevisiae that controls the expression of the alcohol dehydrogenase 2 gene. Its activity is tightly regulated by glucose levels, exhibiting repression during high glucose conditions and strong induction during glucose depletion, making it a key component in metabolic and synthetic biology applications. Due to its glucose-repressible nature, the ADH2 promoter is frequently employed in metabolic engineering strategies to drive gene expression in the later stages of fermentation, allowing for a temporal control. | ||
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Revision as of 16:59, 20 September 2024
ADH2 promoter (Saccharomyces cerevisiae)
The ADH2 promoter is a well-characterized and widely used regulatory element in Saccharomyces cerevisiae that controls the expression of the alcohol dehydrogenase 2 gene. Its activity is tightly regulated by glucose levels, exhibiting repression during high glucose conditions and strong induction during glucose depletion, making it a key component in metabolic and synthetic biology applications. Due to its glucose-repressible nature, the ADH2 promoter is frequently employed in metabolic engineering strategies to drive gene expression in the later stages of fermentation, allowing for a temporal control.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]