Difference between revisions of "Part:BBa K5036002"
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__NOTOC__ | __NOTOC__ | ||
<partinfo>BBa_K5036002 short</partinfo> | <partinfo>BBa_K5036002 short</partinfo> | ||
| − | + | ==Part Description== | |
It is a nuclear localization signal which is a short sequence of amino acids found in certain proteins that acts as a zip code, directing those proteins to the nucleus of a cell. In our model it is attached to dCas9(C) to keep it in the nucleus to avoid dCas9 self assembly. | It is a nuclear localization signal which is a short sequence of amino acids found in certain proteins that acts as a zip code, directing those proteins to the nucleus of a cell. In our model it is attached to dCas9(C) to keep it in the nucleus to avoid dCas9 self assembly. | ||
| + | ==Usage== | ||
| + | This part is attached to dCas9(C) to prevent its assembly with dCas9(N) and control of transcription activity. | ||
| + | |||
<!-- Add more about the biology of this part here | <!-- Add more about the biology of this part here | ||
Revision as of 17:15, 9 September 2024
NLS
Part Description
It is a nuclear localization signal which is a short sequence of amino acids found in certain proteins that acts as a zip code, directing those proteins to the nucleus of a cell. In our model it is attached to dCas9(C) to keep it in the nucleus to avoid dCas9 self assembly.
Usage
This part is attached to dCas9(C) to prevent its assembly with dCas9(N) and control of transcription activity.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]