Difference between revisions of "Part:BBa K5198000"
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Revision as of 07:35, 25 August 2024
CD19ecto
Ectodomain of human CD19 coreceptor. In its native form, CD19 is a coreceptor in the B-cell antigen receptor complex on B-lymphocytes. CD19 is used as a marker of B-cell development and is one of the most popular targets in cell therapies treating most types of leukemia. This part can be used as a soluble ligand that triggers activation of receptors capable of dimerization. CD19ecto has been shown to exist in monomeric and dimeric form. The dimer form is suggested to be responsible for activation of receptors.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000INCOMPATIBLE WITH RFC[1000]Illegal BsaI.rc site found at 225
Illegal SapI.rc site found at 61