Difference between revisions of "Part:BBa K243027"

Revision as of 22:21, 20 October 2009

His-FOS

Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. The heterodimeric Fos complex is one of the nine homologues of the AP-1 leucine zipper region. Via leucin zipper they interact among each other and with their bipartite domain they bind DNA. (Abate et al., Mol Cell Biol. 1991 July).

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BamHI site found at 19
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 2: / Line 2: @@
 <partinfo>BBa_K243027 short</partinfo><br>
-Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. The heterodimeric Fos complex is one of the nine homologues of the AP-1 leucine zipper region.
+Activator protein-1 (AP-1) is a crucial transcription factor implicated in numerous cancers. The heterodimeric Fos complex is one of the nine homologues of the AP-1 leucine zipper region. Via leucin zipper they interact among each other and with their bipartite domain they bind DNA. (Abate et al., Mol Cell Biol. 1991 July).
+[[Image:1fos bio r 250.jpg]]
-The heterodimeric Fos complex is a transcriptional activator involved in the signal transduction pathway. Via leucin zipper they interact among each other and with their bipartite domain, rich of basic amino acids, they bind DNA [[Image:1fos bio r 250.jpg]](Abate et al., Mol Cell Biol. 1991 July).
 <!-- Add more about the biology of this part here