Difference between revisions of "Part:BBa K4825000"

 
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By accumulating MVA through the over expression of tHMG1, MVA pathway is expressed more efficiently, and the yield of  isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) would increase, which are both precursors of pinene, hence the yield of pinene can be increased. "
 
By accumulating MVA through the over expression of tHMG1, MVA pathway is expressed more efficiently, and the yield of  isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) would increase, which are both precursors of pinene, hence the yield of pinene can be increased. "
  
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Add more about the biology of this part here
 
===Usage and Biology===
 
===Usage and Biology===
  

Revision as of 18:09, 11 October 2023


tHMG1

"HMG1, 3-hydroxy-3-methylglutaryl-CoA reductase, is the endogenous gene in yeast. It can catalyze the conversion from hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonate (MVA). By accumulating MVA through the over expression of tHMG1, MVA pathway is expressed more efficiently, and the yield of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) would increase, which are both precursors of pinene, hence the yield of pinene can be increased. "

Add more about the biology of this part here

Usage and Biology

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 1456
  • 1000
    COMPATIBLE WITH RFC[1000]