Difference between revisions of "Part:BBa K4601005"

Revision as of 15:13, 11 October 2023

NpSRII

This part is the NpSRII sensory rhodopsin.

Usage and Biology

NpSRII is a sensory rhodopsin identified in the archaea Natronomonas pharaonis.

Sensory rhodopsins are not pumps, but photoreceptors that respond to light and transmit the signal into the cell via a signaling cascade. For this, in N. pharaonis, NpSRI and NpSRII interact with the transducer proteins NpHtrI and NpHtrII, respectively [1]. NpHtrI and NpHtrII are homodimeric membrane proteins that have also a cytoplasmic histidine kinase domain responsible for initiating the signaling cascade that mediates chemotaxis. The interaction between the SR and their cognate Htr transducers are highly specific.

References

[1] Jung KH, Spudich EN, Trivedi VD, Spudich JL. An archaeal photosignal-transducing module mediates phototaxis in Escherichia coli. Journal of Bacteriology (2001) 183: 6365–6371.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal NgoMIV site found at 73
Illegal NgoMIV site found at 331
1000
COMPATIBLE WITH RFC[1000]

@@ Line 3: / Line 3: @@
 <partinfo>BBa_K4601005 short</partinfo>
-to do
+This part is the NpSRII sensory rhodopsin.
-<!-- Add more about the biology of this part here
 ===Usage and Biology===
+NpSRII is a sensory rhodopsin identified in the archaea ''Natronomonas pharaonis''.
+Sensory rhodopsins are not pumps, but photoreceptors that respond to light and transmit the signal into the cell via a signaling cascade. For this, in ''N. pharaonis'', NpSRI and NpSRII interact with the transducer proteins NpHtrI and NpHtrII, respectively [1]. NpHtrI and NpHtrII are homodimeric membrane proteins that have also a cytoplasmic histidine kinase domain responsible for initiating the signaling cascade that mediates chemotaxis. The interaction between the SR and their cognate Htr transducers are highly specific.
+===References===
+[1] Jung KH, Spudich EN, Trivedi VD, Spudich JL. An archaeal photosignal-transducing module mediates phototaxis in ''Escherichia coli''. Journal of Bacteriology (2001) 183: 6365–6371.
 <!-- -->