Difference between revisions of "Part:BBa K200027"

Latest revision as of 17:26, 19 October 2009

PAH+RBS+GFP+TT

Testing construct to assay the production of the PAH enzyme. The PAH enzyme is responsible for the breakdown of phenylalanine into tyrosine. This enzyme is produced by the Human liver and a genetic deficiency of the encoding gene can lead to a condition called Phenylketonuria. This condition causes mental retardation through progessive brain damage caused by the accumulation of Phenylalanine. More detailed information on the enzyme at the main PAH registry page: BBa_K200008.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BglII site found at 287
Illegal BamHI site found at 814
Illegal XhoI site found at 524
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
INCOMPATIBLE WITH RFC[1000]
Illegal BsaI.rc site found at 2032

@@ Line 2: / Line 2: @@
 <partinfo>BBa_K200027 short</partinfo>
-Testing construct to assay the production of the PAH enzyme
+Testing construct to assay the production of the PAH enzyme. The PAH enzyme is responsible for the breakdown of phenylalanine into tyrosine. This enzyme is produced by the Human liver and a genetic deficiency of the encoding gene can lead to a condition called Phenylketonuria. This condition causes mental retardation through progessive brain damage caused by the accumulation of Phenylalanine.
+More detailed information on the enzyme at the main PAH registry page: [https://parts.igem.org/Part:BBa_K200008 BBa_K200008].
 <!-- Add more about the biology of this part here