Difference between revisions of "Part:BBa K4585000"
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− | A protein of truncated gonadotropin-releasing hormone. | + | A protein of truncated gonadotropin-releasing hormone.GnRH secreted by the hypothalamus plays an important role in the regulation of vertebrate reproduction. It is a peptide of 10 amino acids, which can be synthesized artificially. It can release luteinizing hormone and follicle stimulating hormone. It is mainly distributed in the lateral area of median eminence, as well as in arcuate nucleus, preoptic area of hypothalamus, ependymal cells and pineal gland. |
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− | <img width="400px" src="https://static.igem.wiki/teams/4585/wiki/gnrh.png"></p> | + | <img width="400px" src="https://static.igem.wiki/teams/4585/wiki/gnrh-cmoshitu.png"></p> |
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− | <p style="width: 80%;text-align:center;font-size: .9rem; margin: -1rem auto 1rem auto; color: #888;">Fig.1 The model diagram of | + | <p style="width: 80%;text-align:center;font-size: .9rem; margin: -1rem auto 1rem auto; color: #888;">Fig.1 The model diagram of GnRH-C</p> |
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− | <p style="width: 80%;text-align:center;font-size: .9rem; margin: -1rem auto 1rem auto; color: #888;">Fig. | + | <p style="width: 80%;text-align:center;font-size: .9rem; margin: -1rem auto 1rem auto; color: #888;">Fig.2 The agarose gel electrophoresis map of GnRH-C fragment PCR product</p> |
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− | <p> | + | <p>GnRH-C is the result of truncation of full-length GnRH. |
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Revision as of 01:37, 9 October 2023
GnRH-C
A protein of truncated gonadotropin-releasing hormone.GnRH secreted by the hypothalamus plays an important role in the regulation of vertebrate reproduction. It is a peptide of 10 amino acids, which can be synthesized artificially. It can release luteinizing hormone and follicle stimulating hormone. It is mainly distributed in the lateral area of median eminence, as well as in arcuate nucleus, preoptic area of hypothalamus, ependymal cells and pineal gland.
Insulin
We have proved that Insulin can be processed and secreted outside the cell in 293T cells.
1.diagram
Fig.1 The model diagram of GnRH-C
2.Agarose gel electrophoresis map
Fig.2 The agarose gel electrophoresis map of GnRH-C fragment PCR product
3.Caution
GnRH-C is the result of truncation of full-length GnRH.
4.Reference:
[1]Mingqi Xie, Haifeng Ye, Hui Wang.β-cell-mimetic designer cells provide closed-loop glycemic control[J].Science.2016 Dec 9;354(6317):1296-1301.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]