Difference between revisions of "Part:BBa K4665175"

Revision as of 14:14, 8 October 2023

GGGGS linker

This is a flexible linker made of 4 glycine repeats followed by a serine amino acid, typically used for attaching two protein domains of a fusion protein. The glycine-serine linker incorporates both flexible and hydrophilic elements, preventing the formation of secondary structures and reducing the chance that the linker will interfere with the folding and function of the connected protein domains (van Rosmalen et al., 2017).

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

@@ Line 2: / Line 2: @@
 __NOTOC__
 <partinfo>BBa_K4665175 short</partinfo>
+===GGGGS linker===
-This is a flexible linker made of 4 glycine repeats followed by a serine amino acid. It can be used for fusion proteins.
+This is a flexible linker made of 4 glycine repeats followed by a serine amino acid, typically used for attaching two protein domains of a fusion protein. The glycine-serine linker incorporates both flexible and hydrophilic elements, preventing the formation of secondary structures and reducing the chance that the linker will interfere with the folding and function of the connected protein domains (van Rosmalen et al., 2017).
 <!-- Add more about the biology of this part here