Difference between revisions of "Part:BBa K4665170"
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+ | ===Biology and Usage=== | ||
DNA origami is a technique that allows for the fabrication of complex nanostructures through guided DNA folding (Majikes & Liddle, 2021). The process involves designing a long ssDNA molecule, referred to as a scaffold, which acts as a backbone for the assembly. The long strand of ssDNA will then be folded into the wanted format using short ssDNA fragments called staples. Almost any form can be achieved by altering the staples. | DNA origami is a technique that allows for the fabrication of complex nanostructures through guided DNA folding (Majikes & Liddle, 2021). The process involves designing a long ssDNA molecule, referred to as a scaffold, which acts as a backbone for the assembly. The long strand of ssDNA will then be folded into the wanted format using short ssDNA fragments called staples. Almost any form can be achieved by altering the staples. | ||
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+ | ===References=== |
Revision as of 09:10, 8 October 2023
Octahedron DNA-origami (3024bp long; 42bp edges)
Biology and Usage
DNA origami is a technique that allows for the fabrication of complex nanostructures through guided DNA folding (Majikes & Liddle, 2021). The process involves designing a long ssDNA molecule, referred to as a scaffold, which acts as a backbone for the assembly. The long strand of ssDNA will then be folded into the wanted format using short ssDNA fragments called staples. Almost any form can be achieved by altering the staples. To get the ssDNA sequence a pScaf phagemid with insert for generating DNA origami was used.
Sequence and Features
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal PstI site found at 919
- 12INCOMPATIBLE WITH RFC[12]Illegal PstI site found at 919
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 738
Illegal BglII site found at 1310 - 23INCOMPATIBLE WITH RFC[23]Illegal PstI site found at 919
- 25INCOMPATIBLE WITH RFC[25]Illegal PstI site found at 919
Illegal NgoMIV site found at 132 - 1000COMPATIBLE WITH RFC[1000]