Difference between revisions of "Part:BBa K4634014"

 
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<partinfo>BBa_K4634014 parameters</partinfo>
 
<partinfo>BBa_K4634014 parameters</partinfo>
 
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===References===
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[1] Movva NR, Nakamura K, Inouye M. Amino acid sequence of the signal peptide of ompA protein, a major outer membrane protein of Escherichia coli. J Biol Chem. 1980 Jan 10;255(1):27-9. PMID: 6985608.<br/>
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[2] Pechsrichuang P, Songsiriritthigul C, Haltrich D, Roytrakul S, Namvijtr P, Bonaparte N, Yamabhai M. OmpA signal peptide leads to heterogenous secretion of B. subtilis chitosanase enzyme from E. coli expression system. Springerplus. 2016 Jul 28;5(1):1200. doi: 10.1186/s40064-016-2893-y. PMID: 27516938; PMCID: PMC4963352.

Revision as of 05:25, 7 October 2023


OmpA signal peptide

The OmpA signal peptide is a short amino acid sequence found at the N-terminus of the OmpA protein in Gram-negative bacteria. The primary function of the OmpA signal peptide is to guide the nascent OmpA protein to the appropriate cellular compartment, which is the outer membrane in this case. The signal peptide acts as a recognition signal for the protein translocation machinery present in the bacterial cell. When fused to the N-terminus of other proteins, it has the ability to facilitate the secretion of those proteins.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

[1] Movva NR, Nakamura K, Inouye M. Amino acid sequence of the signal peptide of ompA protein, a major outer membrane protein of Escherichia coli. J Biol Chem. 1980 Jan 10;255(1):27-9. PMID: 6985608.
[2] Pechsrichuang P, Songsiriritthigul C, Haltrich D, Roytrakul S, Namvijtr P, Bonaparte N, Yamabhai M. OmpA signal peptide leads to heterogenous secretion of B. subtilis chitosanase enzyme from E. coli expression system. Springerplus. 2016 Jul 28;5(1):1200. doi: 10.1186/s40064-016-2893-y. PMID: 27516938; PMCID: PMC4963352.