Difference between revisions of "Part:BBa K4890001"
 
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<partinfo>BBa_K4890001 short</partinfo>
 
<partinfo>BBa_K4890001 short</partinfo>
  
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Gene of the metal response element binding transcription Factor-1, a Cys2-His2 zinc finger protein.
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This part is MTF-1 gene derived from Drosophila melanogaster. It encodes MTF-1 (metal-responsive transcription factor-1) which is a transcription factor. MTF-1 protein can be activated by heavy metals. In the cell nucleus of Drosophila cells, MTF-1 binds to MRE to recruit RNA polymerase, in turn increasing the expression of Mto/Mtn to detoxicate metals.  
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Latest revision as of 10:19, 5 October 2023


MTF1

This part is MTF-1 gene derived from Drosophila melanogaster. It encodes MTF-1 (metal-responsive transcription factor-1) which is a transcription factor. MTF-1 protein can be activated by heavy metals. In the cell nucleus of Drosophila cells, MTF-1 binds to MRE to recruit RNA polymerase, in turn increasing the expression of Mto/Mtn to detoxicate metals.

Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal EcoRI site found at 9
    Illegal EcoRI site found at 1923
    Illegal PstI site found at 1681
    Illegal PstI site found at 1859
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal EcoRI site found at 9
    Illegal EcoRI site found at 1923
    Illegal NheI site found at 136
    Illegal PstI site found at 1681
    Illegal PstI site found at 1859
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal EcoRI site found at 9
    Illegal EcoRI site found at 1923
    Illegal BglII site found at 154
    Illegal BamHI site found at 106
    Illegal BamHI site found at 1095
    Illegal BamHI site found at 1491
    Illegal BamHI site found at 1518
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal EcoRI site found at 9
    Illegal EcoRI site found at 1923
    Illegal PstI site found at 1681
    Illegal PstI site found at 1859
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal EcoRI site found at 9
    Illegal EcoRI site found at 1923
    Illegal PstI site found at 1681
    Illegal PstI site found at 1859
    Illegal NgoMIV site found at 1357
  • 1000
    COMPATIBLE WITH RFC[1000]