Difference between revisions of "Part:BBa K4882001"

 
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<partinfo>BBa_K4882001 short</partinfo>
 
<partinfo>BBa_K4882001 short</partinfo>
  
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An insect-specific neurotoxin.
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LqhIT2 is a 61 amino acid-long scorpion depressant toxin from L. quinquestriatus hebraeus. Although the scorpion is dangerous to humans, LqhIT2 is not. LqhIT2 shows a high preference for insect voltage-gated sodium channels and is totally harmless to mammals (Karbat et al., 2007; Zlotkin et al., 1991).
  
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===Usage and Biology===
 
===Usage and Biology===
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Since LqhIT2 is only toxic to insects, it is a good choice for pesticides. To improve the efficiency and effectiveness of Metarhizium anisopliae as a fungal biopesticide, we chose to introduce LqhIT2 into the fungus. LqhIT2 significantly improved the virulence of M. anisopliae against pests.
  
 
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Revision as of 12:32, 4 October 2023


LqhIT2, an insect-specific toxin from Leiurus quinquestriatus hebraeus

LqhIT2 is a 61 amino acid-long scorpion depressant toxin from L. quinquestriatus hebraeus. Although the scorpion is dangerous to humans, LqhIT2 is not. LqhIT2 shows a high preference for insect voltage-gated sodium channels and is totally harmless to mammals (Karbat et al., 2007; Zlotkin et al., 1991).

Usage and Biology

Since LqhIT2 is only toxic to insects, it is a good choice for pesticides. To improve the efficiency and effectiveness of Metarhizium anisopliae as a fungal biopesticide, we chose to introduce LqhIT2 into the fungus. LqhIT2 significantly improved the virulence of M. anisopliae against pests.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BamHI site found at 88
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]