Difference between revisions of "Part:BBa K4839006"
Line 6: Line 6:
  
 
<div style="text-align: center;">
 
<div style="text-align: center;">
−
<html><img src="https://static.igem.wiki/teams/4839/wiki/parts-files/1-1.png" width="350"</html>
+
<html><img src="https://static.igem.wiki/teams/4839/wiki/parts-files/6-1.png" width="350"</html>
 
</div>
 
</div>
−
 
  
 
<p align="center">Figure1. The function of anti-GFP BioPROTAC</p>
 
<p align="center">Figure1. The function of anti-GFP BioPROTAC</p>

Revision as of 14:22, 3 October 2023


vhhGFP4 (GFP Antibody frgement)

We firstly make use of the vhhGFP4, an efficient anti-GFP antibody peptide as our preliminary validation. vhhGFP4 can specifically target to the GFP-IRF4 protein, and then the SPOP component will recruit the ubiquitin and initiate the ubiquitination of GFP-IRF4, which will subsequently led to the degradation of this target protein (Figure 1). We prove this process through our experiment.

Figure1. The function of anti-GFP BioPROTAC

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]