Difference between revisions of "Part:BBa K4665120"
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| + | This part encodes the zinc metalloenzyme carbonic anhydrase derived from the thermophilic bacterium Sulfurihydrogenibium azorense (SazCA). SazCA facilitates the reversible hydration of carbon dioxide to bicarbonate and protons (CO2 + H2O -><- HCO3 + H+) (De Simone et al, 2015). To date, SazCA is the fastest known carbonic anhydrase with an enzymatic efficacy of kcat/KM = 3.5 × 108 M−1 s−1 (De Luca et al., 2015). | ||
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| + | De Luca, V. et al. (March 15, 2013). An α-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO2 hydration reaction. Bioorganic & Medicinal Chemistry Letters, 21(6): 1465.1469. https://doi.org/10.1016/j.bmc.2012.09.047 | ||
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| + | De Simone, G., et al. (May 1, 2015). Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense. Bioorganic & Medicinal Chemistry Letters, 1;25(9): 2002-2006. https://doi.org/10.1016/j.bmcl.2015.02.068 | ||
Revision as of 09:02, 28 September 2023
This part encodes the zinc metalloenzyme carbonic anhydrase derived from the thermophilic bacterium Sulfurihydrogenibium azorense (SazCA). SazCA facilitates the reversible hydration of carbon dioxide to bicarbonate and protons (CO2 + H2O -><- HCO3 + H+) (De Simone et al, 2015). To date, SazCA is the fastest known carbonic anhydrase with an enzymatic efficacy of kcat/KM = 3.5 × 108 M−1 s−1 (De Luca et al., 2015).
De Luca, V. et al. (March 15, 2013). An α-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO2 hydration reaction. Bioorganic & Medicinal Chemistry Letters, 21(6): 1465.1469. https://doi.org/10.1016/j.bmc.2012.09.047
De Simone, G., et al. (May 1, 2015). Crystal structure of the most catalytically effective carbonic anhydrase enzyme known, SazCA from the thermophilic bacterium Sulfurihydrogenibium azorense. Bioorganic & Medicinal Chemistry Letters, 1;25(9): 2002-2006. https://doi.org/10.1016/j.bmcl.2015.02.068