Difference between revisions of "Part:BBa K4814000"
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<h1>The aha biofilm reducing protein</h1>
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<h1>The hha biofilm reducing protein</h1>
 
<p><span style="color: rgb(0, 0, 0);font-size: 12pt;">Hha is a biofilm reducing protein which decreases initial biofilm formation (</span><span style="color: rgb(33, 33, 33);background-color: rgb(255, 255, 255);font-size: 12pt;">Hong, S. H., Lee, J., &amp; Wood, T. K., 2010)</span><span style="color: rgb(0, 0, 0);font-size: 12pt;">. Hha is a protein of the Hha family, and it is very similar to YmoA protein from&nbsp;</span><span style="color: rgb(33, 33, 33);background-color: rgb(255, 255, 255);font-size: 12pt;">Yersinia enterocolitica (Balsalobre, C., et al., 1996).&nbsp;</span><span style="color: rgb(0, 0, 0);font-size: 12pt;">&nbsp;Evidence has shown that hha interacts with H-NS, a type of chromatin-associated protein, which then expresses virulence factors (Madrid, C., Nieto, J. M., &amp; Ju&aacute;rez, A., 2001). By using this protein, the bacteria will kill itself. This part is used together with RecA (BBa_K629001) to form a composite part (BBa_K4814001).</span></p>
 
<p><span style="color: rgb(0, 0, 0);font-size: 12pt;">Hha is a biofilm reducing protein which decreases initial biofilm formation (</span><span style="color: rgb(33, 33, 33);background-color: rgb(255, 255, 255);font-size: 12pt;">Hong, S. H., Lee, J., &amp; Wood, T. K., 2010)</span><span style="color: rgb(0, 0, 0);font-size: 12pt;">. Hha is a protein of the Hha family, and it is very similar to YmoA protein from&nbsp;</span><span style="color: rgb(33, 33, 33);background-color: rgb(255, 255, 255);font-size: 12pt;">Yersinia enterocolitica (Balsalobre, C., et al., 1996).&nbsp;</span><span style="color: rgb(0, 0, 0);font-size: 12pt;">&nbsp;Evidence has shown that hha interacts with H-NS, a type of chromatin-associated protein, which then expresses virulence factors (Madrid, C., Nieto, J. M., &amp; Ju&aacute;rez, A., 2001). By using this protein, the bacteria will kill itself. This part is used together with RecA (BBa_K629001) to form a composite part (BBa_K4814001).</span></p>
 
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Revision as of 10:50, 25 September 2023

The hha biofilm reducing protein

Hha is a biofilm reducing protein which decreases initial biofilm formation (Hong, S. H., Lee, J., & Wood, T. K., 2010). Hha is a protein of the Hha family, and it is very similar to YmoA protein from Yersinia enterocolitica (Balsalobre, C., et al., 1996).  Evidence has shown that hha interacts with H-NS, a type of chromatin-associated protein, which then expresses virulence factors (Madrid, C., Nieto, J. M., & Juárez, A., 2001). By using this protein, the bacteria will kill itself. This part is used together with RecA (BBa_K629001) to form a composite part (BBa_K4814001).


Balsalobre, C., Juárez, A., Madrid, C., Mouriño, M., Prenafeta, A., & Muñoa, F. J. (1996). Complementation of the hha mutation in Escherichia coli by the ymoA gene from Yersinia enterocolitica: dependence on the gene dosage. Microbiology (Reading, England), 142 ( Pt 7), 1841–1846. https://doi.org/10.1099/13500872-142-7-1841


Hong, S. H., Lee, J., & Wood, T. K. (2010). Engineering global regulator Hha of Escherichia coli to control biofilm dispersal. Microbial biotechnology, 3(6), 717–728. https://doi.org/10.1111/j.1751-7915.2010.00220.x


Madrid, C., Nieto, J. M., & Juárez, A. (2001). Role of the Hha/YmoA family of proteins in the thermoregulation of the expression of virulence factors. International Journal of Medical Microbiology, 291(6-7), 425-432. https://doi.org/10.1078/1438-4221-00149




Sequence derived from: https://www.uniprot.org/uniprotkb/P0ACE6/entry