Difference between revisions of "Part:BBa K4586008"
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==Part Description==
 
==Part Description==
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it has a hairpin structure which has high affinity for MCP
+
This part is a highly specific RNA hairpin loop structure that has high affinity for MCP to navigate the MCP-ADAR2 to the sequence of interest by flanking the sequence with two MS2 hairpin structures.
 +
 
 
==Usage==
 
==Usage==
 
This part is used in our design to direct the activity of MCP-ADAR2  to the sensor sequence that is flanked by two MS2 hairpin structures by the RNA binding domain MS2 coat protein (MCP).  Therefore, the sensitivity of this system is markedly enhanced.
 
This part is used in our design to direct the activity of MCP-ADAR2  to the sensor sequence that is flanked by two MS2 hairpin structures by the RNA binding domain MS2 coat protein (MCP).  Therefore, the sensitivity of this system is markedly enhanced.

Revision as of 13:05, 20 September 2023


MS2

Part Description

This part is a highly specific RNA hairpin loop structure that has high affinity for MCP to navigate the MCP-ADAR2 to the sequence of interest by flanking the sequence with two MS2 hairpin structures.

Usage

This part is used in our design to direct the activity of MCP-ADAR2 to the sensor sequence that is flanked by two MS2 hairpin structures by the RNA binding domain MS2 coat protein (MCP). Therefore, the sensitivity of this system is markedly enhanced. Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]