Difference between revisions of "Part:BBa K4586006"
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==Part Description== | ==Part Description== | ||
| − | + | Our guide RNA part is a specific RNA fragment that navigates the Cas system to the RNA or DNA target of interest according to its family and serves to make some changes, such as deletion, insertion, or alteration, to the target RNA or DNA by building complexes with them. | |
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==Usage== | ==Usage== | ||
Our guide RNA is designed to drive the activity of the Cas12k protein toward the target gene, which is the B-cell activating factor receptor (BAFF-R) gene, as knocking down this gene will affect the survival of the autoreactive B-cells and limit its pathogenic effect in RA | Our guide RNA is designed to drive the activity of the Cas12k protein toward the target gene, which is the B-cell activating factor receptor (BAFF-R) gene, as knocking down this gene will affect the survival of the autoreactive B-cells and limit its pathogenic effect in RA | ||
Revision as of 12:24, 20 September 2023
Guide RNA
Part Description
Our guide RNA part is a specific RNA fragment that navigates the Cas system to the RNA or DNA target of interest according to its family and serves to make some changes, such as deletion, insertion, or alteration, to the target RNA or DNA by building complexes with them.
Usage
Our guide RNA is designed to drive the activity of the Cas12k protein toward the target gene, which is the B-cell activating factor receptor (BAFF-R) gene, as knocking down this gene will affect the survival of the autoreactive B-cells and limit its pathogenic effect in RA
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]