Difference between revisions of "Part:BBa K4656002"
(→Usage and Biology) |
|||
| Line 12: | Line 12: | ||
===Usage and Biology=== | ===Usage and Biology=== | ||
As a neurotransmitter, serotonin can play the role of intestinal motility. If its secretion is insufficient, it can easily lead to the decline of intestinal motility, and then lead to chronic constipation. Therefore, promoting TPH expression is conducive to the treatment of chronic constipation. | As a neurotransmitter, serotonin can play the role of intestinal motility. If its secretion is insufficient, it can easily lead to the decline of intestinal motility, and then lead to chronic constipation. Therefore, promoting TPH expression is conducive to the treatment of chronic constipation. | ||
| + | <html><BR><BR><center><img style="display: block;-webkit-user-select: none;margin: auto;cursor: zoom-in;background-color: hsl(0,0%,90%);transition: background-color 300ms;" src="https://static.igem.wiki/teams/4656/wiki/part-plam-tph-tdc.jpg" width="600" height="300"></center></html> | ||
===Sequence and Features=== | ===Sequence and Features=== | ||
Revision as of 15:15, 11 September 2023
TPH
Tph also plays an important role in the synthesis of serotonin, in which the rate-limiting step is catalyzed by TPH，converting tryptophan (an essential amino acid) to 5-hydroxytryptophan (5-HTP).
Usage and Biology
As a neurotransmitter, serotonin can play the role of intestinal motility. If its secretion is insufficient, it can easily lead to the decline of intestinal motility, and then lead to chronic constipation. Therefore, promoting TPH expression is conducive to the treatment of chronic constipation.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 898
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 673
- 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 240