Difference between revisions of "Part:BBa K4501009"
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This part encodes for a ligand of CD19, a surface marker of B cells. It speciffically encodes for the active extracellular domain of the ligand, with no transmembrane nor cytosolic domain. Structure was obtained by homology approximation and then cytosolic and transmembrane domains were removed for it to be attached as a fusion protein. | This part encodes for a ligand of CD19, a surface marker of B cells. It speciffically encodes for the active extracellular domain of the ligand, with no transmembrane nor cytosolic domain. Structure was obtained by homology approximation and then cytosolic and transmembrane domains were removed for it to be attached as a fusion protein. | ||
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+ | [[File:Docksimple.jpg]] | ||
+ | Figure 1. Image of the surface interaction of CD19-L (blue) with CD19 (red). | ||
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Latest revision as of 11:32, 12 October 2022
CD19-L
This part encodes for a ligand of CD19, a surface marker of B cells. It speciffically encodes for the active extracellular domain of the ligand, with no transmembrane nor cytosolic domain. Structure was obtained by homology approximation and then cytosolic and transmembrane domains were removed for it to be attached as a fusion protein.
Figure 1. Image of the surface interaction of CD19-L (blue) with CD19 (red).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 97
Illegal NgoMIV site found at 340 - 1000INCOMPATIBLE WITH RFC[1000]Illegal SapI.rc site found at 42