Difference between revisions of "Part:BBa K4365029"

 
 
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<partinfo>BBa_K4365029 short</partinfo>
 
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Codon optimized VEGF for yeast expression.
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This part contains yeast codon-optimized human VEGF-A (vascular endothelial growth factor). VEGF-A is a 165-aminoacids long (45kDa) secreted dimeric protein. In mammals, VEGF-A acts as an angiogenic factor and stimulates the growth and migration of endothelial cells<ref>Apte RS, Chen DS, Ferrara N. VEGF in Signaling and Disease: Beyond Discovery and Development. Cell. 2019 Mar 7;176(6):1248-1264. doi: 10.1016/j.cell.2019.01.021. PMID: 30849371; PMCID: PMC6410740.</ref>.
  
 
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<partinfo>BBa_K4365029 parameters</partinfo>
 
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===References===

Latest revision as of 08:46, 12 October 2022


VEGF

This part contains yeast codon-optimized human VEGF-A (vascular endothelial growth factor). VEGF-A is a 165-aminoacids long (45kDa) secreted dimeric protein. In mammals, VEGF-A acts as an angiogenic factor and stimulates the growth and migration of endothelial cells[1].

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 67
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

  1. ↑ Apte RS, Chen DS, Ferrara N. VEGF in Signaling and Disease: Beyond Discovery and Development. Cell. 2019 Mar 7;176(6):1248-1264. doi: 10.1016/j.cell.2019.01.021. PMID: 30849371; PMCID: PMC6410740.