Difference between revisions of "Part:BBa K4165188"
 
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<partinfo>BBa_K4165188 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K4165188 SequenceAndFeatures</partinfo>
  
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===Dry Lab Characterization===
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<p style=" font-weight: bold; font-size:14px;"> Modeling </p>
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The peptide was modeled by several software (Alphafold-Apptest-Pepfold) and the best model from Alphafold scored 3 out of 6 according to our Quality assessment code.
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<p><img src="https://static.igem.wiki/teams/4165/wiki/parts-registry/mix.png" style="margin-left:200px;" alt="" width="500" /></p>
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                        Figure 1. The 3D structure of peptide AB(39-42)-CLPFFD modeled by Alphafold
  
 
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Latest revision as of 19:24, 11 October 2022


Amyloid beta peptide 8

This part encodes two Amyloid 𝛽 peptides (BBa_K4165186) and (BBa_K4165187) conjugated together. It has the ability to bind to A𝛽 plaques inside the brain.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Dry Lab Characterization

Modeling

The peptide was modeled by several software (Alphafold-Apptest-Pepfold) and the best model from Alphafold scored 3 out of 6 according to our Quality assessment code. 

                       Figure 1. The 3D structure of peptide AB(39-42)-CLPFFD modeled by Alphafold