Difference between revisions of "Part:BBa K4335003:Design"
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<partinfo>BBa_K4335003 SequenceAndFeatures</partinfo> | <partinfo>BBa_K4335003 SequenceAndFeatures</partinfo> | ||
+ | BBa_K4335003 is a resistance gene optimized for Chlamydomonas reinhardtii based on the original gene. We inserted a 145bp intron into the original gene to facilitate its expression in Chlamydomonas reinhardtii.<br> | ||
+ | <br> | ||
===Design Notes=== | ===Design Notes=== |
Latest revision as of 17:41, 11 October 2022
ChlamyHgR
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 782
Illegal NgoMIV site found at 890 - 1000COMPATIBLE WITH RFC[1000]
BBa_K4335003 is a resistance gene optimized for Chlamydomonas reinhardtii based on the original gene. We inserted a 145bp intron into the original gene to facilitate its expression in Chlamydomonas reinhardtii.
Design Notes
In order to make it easier to heterologously express in Chlamydomonas reinhardtii, we have optimized the codon and added a segment of the intron.
Source
Photoreceptor Genes in Chlamydomonas reinhardtii via Zinc-Finger Nucleases and CRISPR/Cas9. Plant Cell 29, 2498-2518. Hirano, M., Ando, R., Shimozono, S., Sugiyama, M., Takeda, N., Kurokawa, H., Deguchi, R., Endo, K., Haga, K., Takai-Todaka, R., et al. (2022). A highly photostable and bright green fluorescent protein. Nat Biotechnol 40, 1132-1142.