Difference between revisions of "Part:BBa K4256111"
SunJi UCAS (Talk | contribs) |
SunJi UCAS (Talk | contribs) |
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| + | __NOTOC__ | ||
| + | <partinfo>BBa_K4256111 short</partinfo> | ||
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It is a component of the CcdA/CcdB Type II Toxin-antitoxin (TA) system. It encodes the CcdA antidote, which can prevent CcdB toxicity by forming a tight CcdA-CcdB complex. As a model system, by ensuring an antidote-toxin ratio greater than one, this mechanism might prevent the harmful effect of CcdB in plasmid-containing bacteria. The CcdA-CcdB toxin-antitoxin system we used is a killing switch that is relatively nontoxic to human and other mammalian cells. | It is a component of the CcdA/CcdB Type II Toxin-antitoxin (TA) system. It encodes the CcdA antidote, which can prevent CcdB toxicity by forming a tight CcdA-CcdB complex. As a model system, by ensuring an antidote-toxin ratio greater than one, this mechanism might prevent the harmful effect of CcdB in plasmid-containing bacteria. The CcdA-CcdB toxin-antitoxin system we used is a killing switch that is relatively nontoxic to human and other mammalian cells. | ||
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| + | <!-- Add more about the biology of this part here | ||
| + | ===Usage and Biology=== | ||
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| + | <!-- --> | ||
| + | <span class='h3bb'>Sequence and Features</span> | ||
| + | <partinfo>BBa_K4256111 SequenceAndFeatures</partinfo> | ||
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| + | <!-- Uncomment this to enable Functional Parameter display | ||
| + | ===Functional Parameters=== | ||
| + | <partinfo>BBa_K4256111 parameters</partinfo> | ||
| + | <!-- --> | ||
Latest revision as of 16:19, 11 October 2022
ccdA
It is a component of the CcdA/CcdB Type II Toxin-antitoxin (TA) system. It encodes the CcdA antidote, which can prevent CcdB toxicity by forming a tight CcdA-CcdB complex. As a model system, by ensuring an antidote-toxin ratio greater than one, this mechanism might prevent the harmful effect of CcdB in plasmid-containing bacteria. The CcdA-CcdB toxin-antitoxin system we used is a killing switch that is relatively nontoxic to human and other mammalian cells.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]