Difference between revisions of "Part:BBa K4117222:Experience"
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===Applications of BBa_K4117222=== | ===Applications of BBa_K4117222=== | ||
| + | UGT1A3 plays an significant role in metabolic section, working upon the sensing section. Tetrahydrocannabinol (Δ9 -THC), the primary psychoactive ingredient in marijuana, is subject to cytochrome P450 oxidation and subsequent UDP-glucuronosyltransferase(UGT)-dependent glucuronidation. Many studies have shown that CYP2C9 and CYP2C19 are the primary enzymes responsible for these cytochrome P450-dependent oxidations.The specific human UGTs are responsible for classic cannabinoid metabolism, and among them, the highest activity toward THC-COOH was observed with UGT1A3. | ||
===User Reviews=== | ===User Reviews=== | ||
Revision as of 16:16, 11 October 2022
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Applications of BBa_K4117222
UGT1A3 plays an significant role in metabolic section, working upon the sensing section. Tetrahydrocannabinol (Δ9 -THC), the primary psychoactive ingredient in marijuana, is subject to cytochrome P450 oxidation and subsequent UDP-glucuronosyltransferase(UGT)-dependent glucuronidation. Many studies have shown that CYP2C9 and CYP2C19 are the primary enzymes responsible for these cytochrome P450-dependent oxidations.The specific human UGTs are responsible for classic cannabinoid metabolism, and among them, the highest activity toward THC-COOH was observed with UGT1A3.
User Reviews
UNIQdf191c8c5da8c032-partinfo-00000000-QINU UNIQdf191c8c5da8c032-partinfo-00000001-QINU