Difference between revisions of "Part:BBa K4156086"
 
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===Usage and Biology===
 
===Usage and Biology===
  
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It activates host immune response through recruitment of T cells and dendritic cells.CCL21 is used as a therapeutic component to confer therapeutic capability to engineered strains against CRC tumor cells.
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It activates host immune response through recruitment of T cells and dendritic cells.<sup>[1]</sup> CCL21 is used as a therapeutic component to confer therapeutic capability to engineered strains against CRC tumor cells.
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===References===
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<i>
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1 Loeffler M, Le'Negrate G, Krajewska M, Reed JC. Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth. Cancer Immunol Immunother. May 2009;58(5):769-75. doi:10.1007/s00262-008-0555-9
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</i>
  
 
<span class='h3bb'>Sequence and Features</span>
 
<span class='h3bb'>Sequence and Features</span>

Latest revision as of 11:51, 11 October 2022


CCL21

CCL21 is an anti-tumor protein.


Usage and Biology

It activates host immune response through recruitment of T cells and dendritic cells.[1] CCL21 is used as a therapeutic component to confer therapeutic capability to engineered strains against CRC tumor cells.


References

1 Loeffler M, Le'Negrate G, Krajewska M, Reed JC. Salmonella typhimurium engineered to produce CCL21 inhibit tumor growth. Cancer Immunol Immunother. May 2009;58(5):769-75. doi:10.1007/s00262-008-0555-9

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]