Difference between revisions of "Part:BBa K4165121"
Line 13: Line 13:
 
<partinfo>BBa_K4165121 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K4165121 SequenceAndFeatures</partinfo>
  
−
===Functional Parameters===
 
  
  

Revision as of 13:22, 10 October 2022


HTRA Binding Peptide 27

part encodes for a synthetic peptide that binds to the PDZ domain of HTRA1 protein

Usage and Biology

Synthetic peptide acquired by Phage display, Binds specifically to the water-sites of PDZ domain of HTRA1 Protein with IC50 of 3.3 ± 0.2 and G of 170


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


References

Beuming, T., Farid, R., & Sherman, W. (2009). High‐energy water sites determine peptide binding affinity and specificity of PDZ domains. Protein Science, 18(8), 1609-1619.