Difference between revisions of "Part:BBa K4156094"

 
 
Line 3: Line 3:
 
<partinfo>BBa_K4156094 short</partinfo>
 
<partinfo>BBa_K4156094 short</partinfo>
  
−
To be refined
+
The site that binds specifically to CAP is a sequence that partially overlaps with Plac at the upstream end of the promoter P1ac of the 1ac manipulator element
 +
 
 +
<!-- Add more about the biology of this part here  -->
  
−
<!-- Add more about the biology of this part here
 
 
===Usage and Biology===
 
===Usage and Biology===
  
−
<!-- -->
+
CAP is formed by the combination of CRP and cAMP.When CAP binds to this sequence, it enhances the transcriptional activity of RNA polymerase, resulting in a 50-fold increase in transcription. In contrast, when glucose is available for catabolism, cAMP concentration decreases, CRP cannot be activated, and structural gene expression of the 1ac manipulator element decreases.
 +
 
 +
 
 
<span class='h3bb'>Sequence and Features</span>
 
<span class='h3bb'>Sequence and Features</span>
 
<partinfo>BBa_K4156094 SequenceAndFeatures</partinfo>
 
<partinfo>BBa_K4156094 SequenceAndFeatures</partinfo>

Latest revision as of 08:45, 9 October 2022


CAP binding site

The site that binds specifically to CAP is a sequence that partially overlaps with Plac at the upstream end of the promoter P1ac of the 1ac manipulator element


Usage and Biology

CAP is formed by the combination of CRP and cAMP.When CAP binds to this sequence, it enhances the transcriptional activity of RNA polymerase, resulting in a 50-fold increase in transcription. In contrast, when glucose is available for catabolism, cAMP concentration decreases, CRP cannot be activated, and structural gene expression of the 1ac manipulator element decreases.


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]