Difference between revisions of "Part:BBa K4385010"

 
 
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<partinfo>BBa_K4385010 short</partinfo>
 
<partinfo>BBa_K4385010 short</partinfo>
  
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The copper ion sensor part is composed of PcusC and CusSR two-component membrane associated sensor kinase system. CusSR is composed of membrane-associated histidine kinase CusS and transcription activator CusR, responsible for sensing the presence of external Cu2+. When external copper is sensed, the transmembrane structure of CusS protein undergoes a conformational change, and at the same time, autophosphorylation occurs to transmit the signal into the cell. The phosphoryl group is then transferred to the CusR protein, triggering a conformational change in CusR, and the phosphoryl group binds to a sequence in front of the PcusC promoter to turn on downstream gene expression.
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The part can enhance the tolerance of engineering bacteria to heavy metal solutions, and can be used as a supplement for surface display to improve the adsorption efficiency of engineering bacteria to heavy metal ions.
  
 
<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here

Latest revision as of 13:31, 6 October 2022


Heavy metal detoxification protein

The part can enhance the tolerance of engineering bacteria to heavy metal solutions, and can be used as a supplement for surface display to improve the adsorption efficiency of engineering bacteria to heavy metal ions.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NheI site found at 7
    Illegal NheI site found at 30
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 142
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]