Difference between revisions of "Part:BBa K4165198"
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This part encodes a part of the Amyloid 𝛽 fragment (38-42) which has the ability to bind to A𝛽 plaques inside the brain. | This part encodes a part of the Amyloid 𝛽 fragment (38-42) which has the ability to bind to A𝛽 plaques inside the brain. | ||
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===Usage and Biology=== | ===Usage and Biology=== |
Revision as of 11:23, 6 October 2022
Amyloid beta peptide 18 (Aβ 38-42)
This part encodes a part of the Amyloid 𝛽 fragment (38-42) which has the ability to bind to A𝛽 plaques inside the brain.
Usage and Biology
Type of Amyloid-beta binding peptide start from amino acid 38 to 42, this peptide characterized by its solubility which is 156 ± 33 μm.
Features and codon optimize
This sequence is optimized for E. coli bacteria
Source
Homo sapiens Amyloid-beta precursor protein - UniProt (P05067)
References
1- Zhao, Y., Cai, J., Liu, Z., Li, Y., Zheng, C., Zheng, Y., ... & Liu, Y. (2018). Nanocomposites inhibit the formation, mitigate the neurotoxicity, and facilitate the removal of β-amyloid aggregates in Alzheimer’s disease mice. Nano letters, 19(2), 674-683.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]