Difference between revisions of "Part:BBa K4165198"

Revision as of 11:22, 6 October 2022

Amyloid beta peptide 18 (Aβ 38-42)

This part encodes a part of the Amyloid 𝛽 fragment (38-42) which has the ability to bind to A𝛽 plaques inside the brain.

Sequence and Features

Assembly Compatibility:

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 <!-- Add more about the biology of this part here
 ===Usage and Biology===
+Type of Amyloid-beta binding peptide start from amino acid 38 to 42, this peptide characterized by its solubility which is 156 ± 33 μm.
+===Features and codon optimize===
+This sequence is optimized for E. coli bacteria
+===Source===
+Homo sapiens Amyloid-beta precursor protein - UniProt (P05067)
+===References===
+- Zhao, Y., Cai, J., Liu, Z., Li, Y., Zheng, C., Zheng, Y., ... & Liu, Y. (2018). Nanocomposites inhibit the formation, mitigate the neurotoxicity, and facilitate the removal of β-amyloid aggregates in Alzheimer’s disease mice. Nano letters, 19(2), 674-683.
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