Difference between revisions of "Part:BBa K4140012"
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A proximal sequence element, which attracts the multisubunit component SNAPc, and a TATA box, which recruits the TATA box-binding protein, TBP, make up the human U6 small nuclear RNA core promoter. Two clearly identified factors are necessary for transcription from the human U6 promoter in addition to SNAPc and TBP. The first is the human homologue of the yeast TFIIIB subunit B" (hB), which is generally necessary for the transcription of RNA polymerase III genes, and the second is the human homologue of the TFIIIB subunit BRF (hBRFU), which is one of two human homologues and is specifically necessary for the transcription of U6-type RNA polymerase III promoters. | A proximal sequence element, which attracts the multisubunit component SNAPc, and a TATA box, which recruits the TATA box-binding protein, TBP, make up the human U6 small nuclear RNA core promoter. Two clearly identified factors are necessary for transcription from the human U6 promoter in addition to SNAPc and TBP. The first is the human homologue of the yeast TFIIIB subunit B" (hB), which is generally necessary for the transcription of RNA polymerase III genes, and the second is the human homologue of the TFIIIB subunit BRF (hBRFU), which is one of two human homologues and is specifically necessary for the transcription of U6-type RNA polymerase III promoters. | ||
==Usage== | ==Usage== | ||
| − | + | Human U6 small nuclear RNA core promoter.formed of Two clearly identified factors are necessary for transcription, A proximal sequence element, which attracts the multisubunit component SNAPc, and a TATA box, which recruits the TATA box-binding protein, TBP,Its used to regulate the expression of our regulatory system that is formed of two domains cas12g protein and it’s gRNA which is responsible for tuning of our circuit to prevent over expression of PAH. | |
| − | + | ||
==Literature Characterization== | ==Literature Characterization== | ||
Revision as of 17:55, 28 September 2022
Human U6 promoter
Part Description
A proximal sequence element, which attracts the multisubunit component SNAPc, and a TATA box, which recruits the TATA box-binding protein, TBP, make up the human U6 small nuclear RNA core promoter. Two clearly identified factors are necessary for transcription from the human U6 promoter in addition to SNAPc and TBP. The first is the human homologue of the yeast TFIIIB subunit B" (hB), which is generally necessary for the transcription of RNA polymerase III genes, and the second is the human homologue of the TFIIIB subunit BRF (hBRFU), which is one of two human homologues and is specifically necessary for the transcription of U6-type RNA polymerase III promoters.
Usage
Human U6 small nuclear RNA core promoter.formed of Two clearly identified factors are necessary for transcription, A proximal sequence element, which attracts the multisubunit component SNAPc, and a TATA box, which recruits the TATA box-binding protein, TBP,Its used to regulate the expression of our regulatory system that is formed of two domains cas12g protein and it’s gRNA which is responsible for tuning of our circuit to prevent over expression of PAH.
Literature Characterization
References
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]