Difference between revisions of "Part:BBa K4175000"
(→‎Biology)
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===Biology===
 
===Biology===
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Anti-IL-6 single chain variable fragment (scFv) can bind to interleukin 6 (IL-6). It comprises of a variable heavy chain domain and a variable light chain domain, with a GSG linker joining the two domains. The variable heavy and light chain domain are derived from the human anti-IL-6 monoclonal antibody AME-19a [1].  
+
Anti-IL-6 single chain variable fragment (scFv) can bind to interleukin 6 (IL-6). It comprises of a variable heavy chain domain and a variable light chain domain, with a GSG linker joining the two domains. The variable heavy and light chain domain are derived from the human anti-IL-6 monoclonal antibody AME-19a (Tan et al., 2020).
  
 
===Usage===
 
===Usage===

Revision as of 08:09, 25 September 2022


anti-IL-6 scFv


Sequence and Features


Assembly Compatibility:
  • 10
    INCOMPATIBLE WITH RFC[10]
    Illegal PstI site found at 604
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal PstI site found at 604
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 512
    Illegal XhoI site found at 496
  • 23
    INCOMPATIBLE WITH RFC[23]
    Illegal PstI site found at 604
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal PstI site found at 604
    Illegal AgeI site found at 556
  • 1000
    COMPATIBLE WITH RFC[1000]

Biology

Anti-IL-6 single chain variable fragment (scFv) can bind to interleukin 6 (IL-6). It comprises of a variable heavy chain domain and a variable light chain domain, with a GSG linker joining the two domains. The variable heavy and light chain domain are derived from the human anti-IL-6 monoclonal antibody AME-19a (Tan et al., 2020).

Usage