Difference between revisions of "Part:BBa K3962350"
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<partinfo>BBa_K3962350 short</partinfo> | <partinfo>BBa_K3962350 short</partinfo> | ||
| − | HOK is the toxin of the HOK/SOK toxin-antitoxin system. The HOK/SOK is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The SOK transcript can bind to a homologous region on HOK mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived HOK toxin from the parent cell. Due to the short half-life of the SOK antitoxin, daughter cells inherit only small amounts and it is quickly degraded. | + | HOK is the toxin of the HOK/SOK toxin-antitoxin system. The HOK/SOK is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The SOK transcript can bind to a homologous region on HOK mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived HOK toxin from the parent cell. Due to the short half-life of the SOK antitoxin, daughter cells inherit only small amounts and it is quickly degraded. |
| + | [[Image:https://2021.igem.org/wiki/images/thumb/6/6d/T--Leiden--Parts-HOK.png/800px-T--Leiden--Parts-HOK.png|500px]] | ||
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Revision as of 18:31, 21 October 2021
HOK - Toxin in Hok/Sok
HOK is the toxin of the HOK/SOK toxin-antitoxin system. The HOK/SOK is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The SOK transcript can bind to a homologous region on HOK mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived HOK toxin from the parent cell. Due to the short half-life of the SOK antitoxin, daughter cells inherit only small amounts and it is quickly degraded. 500px
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]