Difference between revisions of "Part:BBa K3885161"
(→Usage and Biology) |
(→Usage and Biology) |
||
Line 38: | Line 38: | ||
</div> | </div> | ||
</html> | </html> | ||
+ | |||
<!-- --> | <!-- --> | ||
<span class='h3bb'>Sequence and Features</span> | <span class='h3bb'>Sequence and Features</span> |
Latest revision as of 12:19, 20 October 2021
CXCL9 mRNA
This part contains a part of CXCL9 mRNA from human beings.
This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded is thought to be involved in T cell trafficking. The encoded protein binds to C-X-C motif chemokine 3 and is a chemoattractant for lymphocytes but not for neutrophils.
Usage and Biology
In the project, we designed igRNA to hybridize with CXCL9 mRNA.
To ensure the hybridization of CXCL9 mRNA and igRNA, we usedNUPACK webserver.to analyze the 2D structure of target RNA.
Table 1. The segment used for testing. The three candidate hybridization regions are marked in green, blue and red. Interacting sequences are underlined.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]