Difference between revisions of "Part:BBa K3846120"

 
 
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<partinfo>BBa_K3846120 short</partinfo>
 
<partinfo>BBa_K3846120 short</partinfo>
  
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This phyto brick features the codon-optimised coding sequence of Hydroxymethylglutaryl-CoA synthase (HMGCS1) from <i>Homo sapiens</i>. This enzyme the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis.
  
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Hydroxymethylglutaryl-CoA synthase (HMGCS1) - MevT Pathway  (phytobrick)
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<b>5' fusion site:</b> TTCG
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<b>3' fusion site:</b> GCTT
  
 
ttcg - gctt
 
ttcg - gctt

Latest revision as of 20:49, 19 October 2021


Hydroxymethylglutaryl-CoA synthase (HMGCS1) - MevT Pathway (phytobrick)

This phyto brick features the codon-optimised coding sequence of Hydroxymethylglutaryl-CoA synthase (HMGCS1) from Homo sapiens. This enzyme the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis.

5' fusion site: TTCG

3' fusion site: GCTT

ttcg - gctt

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]