Difference between revisions of "Part:BBa K3733042"

 
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__NOTOC__
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<partinfo>BBa_K3733042 short</partinfo>
  
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<p>
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Azurin is a copper-containing redox protein secreted by <i>Pseudomonas aeruginosa</i>. Azurin preferentially enters a variety of cancer cells and induces apoptosis or cell cycle arrest, thereby playing an anti-cancer effect. A 6×His tag was added in order to purify the protein.
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PhoA, a signal peptide of Sec pathway in <i>Escherichia coli</i>, have the capability to guide the LL-37 excrete out of the cell.
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</p>
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===Reference===
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Huang F, Qianhui S, Zhaojie Q, et al. Anticancer actions of azurin and its derived peptide p28[J]. The protein journal, 2020, 39(2): 182-189.

Revision as of 16:26, 18 October 2021

PhoA-azurin with a His-tag

Azurin is a copper-containing redox protein secreted by Pseudomonas aeruginosa. Azurin preferentially enters a variety of cancer cells and induces apoptosis or cell cycle arrest, thereby playing an anti-cancer effect. A 6×His tag was added in order to purify the protein. PhoA, a signal peptide of Sec pathway in Escherichia coli, have the capability to guide the LL-37 excrete out of the cell.

Reference

Huang F, Qianhui S, Zhaojie Q, et al. Anticancer actions of azurin and its derived peptide p28[J]. The protein journal, 2020, 39(2): 182-189.