Difference between revisions of "Part:BBa K3999000"
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===Origin: Synthetic=== | ===Origin: Synthetic=== | ||
===Properties: BBa_K3999000 is the coding sequence of tryptophan hydroxylase (TPH), which catalyzes the L-tryptophan to the 5-hydroxy-L-tryptophan=== | ===Properties: BBa_K3999000 is the coding sequence of tryptophan hydroxylase (TPH), which catalyzes the L-tryptophan to the 5-hydroxy-L-tryptophan=== | ||
| + | [[File:T--Shanghai_city--BBa_K3999000- figure1.jpg|500px|thumb|center|Figure1. The protein structure of tryptophan 5-monooxygenase monomer, Human..]] | ||
== Usage and Biology == | == Usage and Biology == | ||
As the rate-limiting enzyme of 5-HT synthesis, TPH plays an important role in invertebrate neuroregulation. In nature, serotonin is widely present in mammalian tissues, especially in the cerebral cortex and nerve synapses, and has a small amount in plants and fungi. In the pharmaceutical field, serotonin, as a drug, can participate in a variety of physiological functions of the organism, including emotion regulation, behaviour management, sleep cycle maintenance, and removal of harmful free radicals. | As the rate-limiting enzyme of 5-HT synthesis, TPH plays an important role in invertebrate neuroregulation. In nature, serotonin is widely present in mammalian tissues, especially in the cerebral cortex and nerve synapses, and has a small amount in plants and fungi. In the pharmaceutical field, serotonin, as a drug, can participate in a variety of physiological functions of the organism, including emotion regulation, behaviour management, sleep cycle maintenance, and removal of harmful free radicals. | ||
Revision as of 09:03, 18 October 2021
TPH
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BamHI site found at 1606
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Profile
Name: TPH
Base Pairs:1641bp
Origin: Synthetic
Properties: BBa_K3999000 is the coding sequence of tryptophan hydroxylase (TPH), which catalyzes the L-tryptophan to the 5-hydroxy-L-tryptophan
Usage and Biology
As the rate-limiting enzyme of 5-HT synthesis, TPH plays an important role in invertebrate neuroregulation. In nature, serotonin is widely present in mammalian tissues, especially in the cerebral cortex and nerve synapses, and has a small amount in plants and fungi. In the pharmaceutical field, serotonin, as a drug, can participate in a variety of physiological functions of the organism, including emotion regulation, behaviour management, sleep cycle maintenance, and removal of harmful free radicals.