Difference between revisions of "Part:BBa K3771010"

Revision as of 07:43, 17 October 2021

Outer Membrane Protein A (OmpA)

Description

Outer membrane protein A (OmpA) is a 35 kDa transmembrane protein found in many enterobacteria. It is responsible for maintaining the stability of the bacterial membrane and cell signaling. [1]

Biology

In E. coli, the β-barrel conformation of OmpA is composed of extracellular loops that help play a role in the detection of outer membrane stress and binding of extracellular molecules. OmpA also serves as a porin channel that regulates water transport within the bacterial cell. [2]

Usage

In our project, the sequence of OmpA protein was used to construct the OmpA/OprF chimeric protein.

               <figure class="d-flex flex-column justify-content-center align-items-center px-lg-3">
               <a href="https://2021.igem.org/File:T--NCKU_Tainan--ompA_oprF.gif" target="_blank" style="width:60%"><img src="https://2021.igem.org/File:T--NCKU_Tainan--ompA_oprF.gif" alt="" title="" style="width:100%"></a>
               </figure>

Sequence and Features