Difference between revisions of "Part:BBa K3962350"

Revision as of 08:07, 16 October 2021

HOK - Toxin in Hok/Sok

Sok is the antitoxin of the Hok/Sok toxin-antitoxin system. The Hok/Sok is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The Sok transcript can bind to a homologous region onHok mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived Hok toxin from the parent cell. Due to the short half-life of the Sok antitoxin, daughter cells inherit only small amounts and it is quickly degraded.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
COMPATIBLE WITH RFC[21]
23
COMPATIBLE WITH RFC[23]
25
COMPATIBLE WITH RFC[25]
1000
COMPATIBLE WITH RFC[1000]

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 <partinfo>BBa_K3962350 short</partinfo>
-Sok is the antitoxin of the Hok/Sok toxin/antitoxin system. The Hok/Sok is a type I toxin/antitoxin system originating from the R1 plasmid in E. coli. The Sok transcript can bind with the leader region of Hok mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived hok toxin from the parent cell. Due to the short half-life of the sok antitoxin, daughter cells inherit only small amounts and it quickly degrades.
+Sok is the antitoxin of the Hok/Sok toxin-antitoxin system. The Hok/Sok is a type I toxin-antitoxin system originating from the R1 plasmid in E. coli. The Sok transcript can bind to a homologous region onHok mRNA and prevent toxin expression. When E. coli undergoes cell division, the two daughter cells inherit the long-lived Hok toxin from the parent cell. Due to the short half-life of the Sok antitoxin, daughter cells inherit only small amounts and it is quickly degraded.
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