Difference between revisions of "Part:BBa K4040007"
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<partinfo>BBa_K4040007 short</partinfo>
 
<partinfo>BBa_K4040007 short</partinfo>
  
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The transmembrane domain of the CAR performs a signal transduction role after the interaction between the S protein of pseudo- SARS-CoV-2 and the CARs. In this part, we used the CD8 hinge and the CD8 transmembrane domain presented in the &#945;CD19 CAR for T cell to construct the transmembrane domain of our CAR-macrophage.
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We use the transmembrane region of human CD8 molecule to build the CARs.
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<!-- Add more about the biology of this part here
 
<!-- Add more about the biology of this part here
 
===Usage and Biology===
 
===Usage and Biology===

Revision as of 00:52, 15 September 2021


CD8 Transmembrane Domain

We use the transmembrane region of human CD8 molecule to build the CARs.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal NgoMIV site found at 22
  • 1000
    COMPATIBLE WITH RFC[1000]