Difference between revisions of "Part:BBa K3392001"
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Cathelicidin peptide is a kind of peptide family protein which can inhibit the protease Cathepsin-L and has antimicrobial effect. Cathelicidin peptide is a kind of peptide family protein which can inhibit the protease cathepsin-l and has anti microbial effect.LL-37 may play an antibacterial role in Hp induced gastritis. | Cathelicidin peptide is a kind of peptide family protein which can inhibit the protease Cathepsin-L and has antimicrobial effect. Cathelicidin peptide is a kind of peptide family protein which can inhibit the protease cathepsin-l and has anti microbial effect.LL-37 may play an antibacterial role in Hp induced gastritis. | ||
| + | <p>LL-37, known as hCAP18 as well, is the C-terminal part of the unique human cathelicidin identified to date named human cationic antimicrobial protein (hCAP). </p> | ||
| + | <p>LL-37 exhibits a variety of immunomodulatory functions such as bactericidal action, chemotaxis, activation of chemokine secretion and antisepsis effect [1].</p> | ||
| + | <p>The synthetic LL-37 peptide has been shown to suppress the inflammatory response induced by LPS and other TLR ligands [2].</p> | ||
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===Usage and Biology=== | ===Usage and Biology=== | ||
Revision as of 01:23, 28 October 2020
LL-37
Cathelicidin peptide is a kind of peptide family protein which can inhibit the protease Cathepsin-L and has antimicrobial effect. Cathelicidin peptide is a kind of peptide family protein which can inhibit the protease cathepsin-l and has anti microbial effect.LL-37 may play an antibacterial role in Hp induced gastritis.
LL-37, known as hCAP18 as well, is the C-terminal part of the unique human cathelicidin identified to date named human cationic antimicrobial protein (hCAP).
LL-37 exhibits a variety of immunomodulatory functions such as bactericidal action, chemotaxis, activation of chemokine secretion and antisepsis effect [1].
The synthetic LL-37 peptide has been shown to suppress the inflammatory response induced by LPS and other TLR ligands [2].
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal XhoI site found at 112
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]