Difference between revisions of "Part:BBa K133071"

Revision as of 00:20, 30 October 2008

UreB

Urease B (UreB)is one of the main H. pylori antigens. It is a subunit of enzyme urease, composed of A and B subunit that neutralizes the pH around the microorganism by decomposing urea into ammonia and carbon dioxide, thus enabling H. pylori to survive in the acidic gastric environment. Application of this antigen should elicit production of neutralizing antibodies thus inhibiting enzymatic activity of urease, which could lead to the eventual eradication of bacteria.

Cloned into pSB1AK3 vector.

Sequence and Features

Assembly Compatibility:

10
COMPATIBLE WITH RFC[10]
12
COMPATIBLE WITH RFC[12]
21
INCOMPATIBLE WITH RFC[21]
Illegal BamHI site found at 1013
23
COMPATIBLE WITH RFC[23]
25
INCOMPATIBLE WITH RFC[25]
Illegal AgeI site found at 235
Illegal AgeI site found at 1413
1000
INCOMPATIBLE WITH RFC[1000]
Illegal SapI.rc site found at 121

@@ Line 1: / Line 1: @@
 __NOTOC__
 <partinfo>BBa_K133071 short</partinfo>
+Urease B (UreB)is one of the main ''H. pylori'' antigens. It is a subunit of enzyme urease, composed of A and B subunit that neutralizes the pH around the microorganism by decomposing urea into ammonia and carbon dioxide, thus enabling H. pylori to survive in the acidic gastric environment. Application of this antigen should elicit production of neutralizing antibodies thus inhibiting enzymatic activity of urease, which could lead to the eventual eradication of bacteria.
 Cloned into pSB1AK3 vector.