Difference between revisions of "Part:BBa K133114"
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<partinfo>BBa_K133114 short</partinfo> | <partinfo>BBa_K133114 short</partinfo> | ||
| − | + | Synthetic multiepitope, comprising the H. pylori urease B epitope, a vacuolating cytotoxin A (Vac) epitope and an adhesin A (HpaA) epitope. UreB epitope comprises AA 314-339 of ''Helicobacter pylori'' urease B, VacA AA 368-487 of vacuolating cytotoxin A of ''Helicobacter pylori'' and HpaA AA 134-146 of''Helicobacter pylori''. B-cell epitopes were designed using available 3D models or structures, which enabled more accurate prediction. Some of them were already shown to elicit antibody production, thus our combination broadens a repertoire of activated B-cells. | |
Revision as of 00:09, 30 October 2008
multiHP-Histop Synthetic multiepitope, comprising the H. pylori urease B epitope, a vacuolating cytotoxin A (Vac) epitope and an adhesin A (HpaA) epitope. UreB epitope comprises AA 314-339 of Helicobacter pylori urease B, VacA AA 368-487 of vacuolating cytotoxin A of Helicobacter pylori and HpaA AA 134-146 ofHelicobacter pylori. B-cell epitopes were designed using available 3D models or structures, which enabled more accurate prediction. Some of them were already shown to elicit antibody production, thus our combination broadens a repertoire of activated B-cells.
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]