Difference between revisions of "Part:BBa K3450020"
 
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Reference
 
Reference
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[1] Simonsen, L., Holst, J.J. & Deacon, C.F. Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs. Diabetologia 49, 706–712 (2006). https://doi.org/10.1007/s00125-005-0128-9
 
[1] Simonsen, L., Holst, J.J. & Deacon, C.F. Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs. Diabetologia 49, 706–712 (2006). https://doi.org/10.1007/s00125-005-0128-9
  

Latest revision as of 16:37, 26 October 2020

Exendin-4

Exendin-4, the dipeptidyl peptidase resistant analogue of GLP-1 was discovered in the venom of a poisonous lizard known as Gila monster (Heloderma suspectum). It has a half-life of about 26 minutes in humans after intravenous infusion which is significantly higher than the half-life of active GLP-1 molecule (1–2 minutes) in humans. [1]

Reference

[1] Simonsen, L., Holst, J.J. & Deacon, C.F. Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs. Diabetologia 49, 706–712 (2006). https://doi.org/10.1007/s00125-005-0128-9

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]