Difference between revisions of "Part:BBa K3396001"
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===Usage and Biology=== | ===Usage and Biology=== | ||
| − | The Coch2[1] module comes from The C. thermocellum scaffoldin and it could recognize and bind tightly to complementary | + | The Coch2[1] module comes from The C. thermocellum scaffoldin and it could recognize and bind tightly to complementary Docs modules harbored by each of the catalytic subunits. The Coh2–DocS pair represents the interaction between two complementary families of protein modules that exhibit divergent specificities and affinities, ranging from one of the highest known affinity constants between two proteins to relatively low-affinity interactions. |
Revision as of 11:42, 26 October 2020
Coh2
The Coch2 module binds DocS (BBa_K3396000) modules constitutively.
Usage and Biology
The Coch2[1] module comes from The C. thermocellum scaffoldin and it could recognize and bind tightly to complementary Docs modules harbored by each of the catalytic subunits. The Coh2–DocS pair represents the interaction between two complementary families of protein modules that exhibit divergent specificities and affinities, ranging from one of the highest known affinity constants between two proteins to relatively low-affinity interactions.
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Reference
[1] BARAK Y, HANDELSMAN T, NAKAR D, et al. Matching fusion protein systems for affinity analysis of two interacting families of proteins: the cohesin-dockerin interaction [J]. J Mol Recognit, 2005, 18(6): 491-501.