Difference between revisions of "Part:BBa K3429001"
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The TasA protein (also known as the major biofilm matrix component) is essential for biofilm structures and polymerizes into long fibers attached to the B. subtilis cells. <sup> [1] </sup> <sup> [2] </sup> <br> We designed TasA fusion proteins with CotA, CuO and EreB to immobilize our degrading enzymes in the biofilm matrix. Protein secretion into the biofilm matrix is regulated by the Sec-dependent signal recognition partice (sec-SRP) pathway. <sup> [3] </sup> | The TasA protein (also known as the major biofilm matrix component) is essential for biofilm structures and polymerizes into long fibers attached to the B. subtilis cells. <sup> [1] </sup> <sup> [2] </sup> <br> We designed TasA fusion proteins with CotA, CuO and EreB to immobilize our degrading enzymes in the biofilm matrix. Protein secretion into the biofilm matrix is regulated by the Sec-dependent signal recognition partice (sec-SRP) pathway. <sup> [3] </sup> | ||
Revision as of 15:34, 25 October 2020
TasA matrix protein
Profile
| Name | TasA matrix protein |
| Base pairs | 786 |
| Molecular weight | 28.15 kDa |
| Origin | Bacillus subtilis |
The TasA protein (also known as the major biofilm matrix component) is essential for biofilm structures and polymerizes into long fibers attached to the B. subtilis cells. [1] [2]
We designed TasA fusion proteins with CotA, CuO and EreB to immobilize our degrading enzymes in the biofilm matrix. Protein secretion into the biofilm matrix is regulated by the Sec-dependent signal recognition partice (sec-SRP) pathway. [3]
References
[1] Branda, S.; Chu, F.; Kearns, D. (2006): A major protein component of the Bacillus subtilis biofilm matrix. In: Molecular microbiology 59 (4), S. 1229–1238, https://doi.org/10.1111/j.1365-2958.2005.05020.x
[2] Romero, D.; Aguilar, C.; Losick, R. (2010): Amyloid fibers provide structural integrity to Bacillus subtilis biofilms. In: Proceedings of the National Academy of Sciences of the United States of America 107 (5), S. 2230–2234, https://doi.org/10.1073/pnas.0910560107x
[3] Stöver, A.; Driks, A. (1999): Secretion, Localization, and Antibacterial Activity of TasA, a Bacillus subtilis Spore-Associated Protein. In: Journal of Bacteriology 181 (5), S. 1664–1672, https://doi.org/10.1128/JB.181.5.1664-1672.1999
Sequence and Features
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]