Difference between revisions of "Part:BBa K3588020"
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The part, when expressed correctly, allows for an increased ability for adherence to antigenic surfaces. The antigenic surface can be any common protein provided the synthetic adhesin VHH region is modified to be complimentary. In this case the VHH region has a complimentary binding site of GFP, and so if GFP is fixed to a surface, such as an ELISA plate then any bacteria expressing a complimentary binding region will be better able to adhere to given surface. This can be seen in the image included here but is better seen through our lab work results: https://2020.igem.org/Team:CLS_CLSG_UK/Results | The part, when expressed correctly, allows for an increased ability for adherence to antigenic surfaces. The antigenic surface can be any common protein provided the synthetic adhesin VHH region is modified to be complimentary. In this case the VHH region has a complimentary binding site of GFP, and so if GFP is fixed to a surface, such as an ELISA plate then any bacteria expressing a complimentary binding region will be better able to adhere to given surface. This can be seen in the image included here but is better seen through our lab work results: https://2020.igem.org/Team:CLS_CLSG_UK/Results | ||
| − | + | https://parts.igem.org/File:T--OFFICIAL_CLS_CLSG_UK--SA_evidence_registry_picture.png#file | |
===properties=== | ===properties=== | ||
Revision as of 16:29, 24 October 2020
Synthetic Adhesin
This part is expressed on the extracellular membrane of E. Coli and from there has a an ability to adhere to an antigenic surface.
function
The part, when expressed correctly, allows for an increased ability for adherence to antigenic surfaces. The antigenic surface can be any common protein provided the synthetic adhesin VHH region is modified to be complimentary. In this case the VHH region has a complimentary binding site of GFP, and so if GFP is fixed to a surface, such as an ELISA plate then any bacteria expressing a complimentary binding region will be better able to adhere to given surface. This can be seen in the image included here but is better seen through our lab work results: https://2020.igem.org/Team:CLS_CLSG_UK/Results https://parts.igem.org/File:T--OFFICIAL_CLS_CLSG_UK--SA_evidence_registry_picture.png#file
